Rachaad White caps a dramatic 20-19 comeback for Tampa Bay in Houston with a 2-yard TD run as six seconds remain. Baker Mayfield lashed two TDs on 25-of-38 for 215 yards, fueling a 2-0 start for the Buccaneers. Houston pressed late behind a punt return and a blocked punt but couldn’t seal it, leaving Nick Chubb's TD run as a late spark. Joe Burrow faces toe surgery and months out; Minnesota’s J.J. McCarthy injures an ankle; Colts sit 2-0. A crowded slate reshapes fantasy value as Chargers and Raiders loom.

Saints fall 26-21 to the 49ers as Spencer Rattler makes his second start while Derek Carr’s shoulder injury and retirement cast a long shadow over New Orleans’ offense.

Rumors link Carr to a possible unretirement trade to Cincinnati during Joe Burrow’s absence, but health concerns and Cincinnati’s preference for Jake Browning make a deal unlikely. New Orleans pursues a youth movement while Week 2 injuries ripple across the league.

The coming weeks will test how quickly Rattler adapts and how aggressively teams adjust around backup QB situations in a league where roster churn is king.